Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses
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چکیده
منابع مشابه
Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug Uses
Drug repositioning has been based largely on genomic signatures of drugs and diseases. One challenge in these efforts lies in connecting the molecular signatures of drugs into clinical responses, including therapeutic and side effects, to the repurpose of drugs. We addressed this challenge by evaluating drug-drug relationships using a phenotypic and molecular-based approach that integrates ther...
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ژورنال
عنوان ژورنال: CPT: Pharmacometrics & Systems Pharmacology
سال: 2016
ISSN: 2163-8306,2163-8306
DOI: 10.1002/psp4.12108